. Author manuscript; available in PMC: 2023 May 1.

Published in final edited form as: Nutr Metab Cardiovasc Dis. 2022 Jan 13;32(5):1218–1226. doi: 10.1016/j.numecd.2022.01.010

Table 3.

Net reclassification improvement with addition of the algorithm to traditional risk factors, determined by 2000x bootstrapping with the validation set.

	TRFs plus algorithm model				TRFs plus algorithm model
	All participants				Top 10 percentile high risk participants in TRFs model
	Number	Individuals reclassified		NRI (%)	Number	Individuals reclassified		NRI (%)
	Number	Increased (%)	Decreased (%)	NRI (%)	Number	Increased (%)	Decreased (%)	NRI (%)

Cases	419	51.5 (46.7–56.4)	48.5 (43.6–53.3)	3.0 (−6.7–12.8)	178	51.7 (36.1–67.4)	48.3 (32.6–63.9)	3.4 (−27.8–34.9)
Non-cases	8889	73.9 (72.9–74.8)	26.1 (25.2–27.1)	47.8 (45.8–49.5)	753	73.9 (70.8–76.8)	26.1 (23.2–29.2)	47.8 (41.6–53.5)
All	9308	-	-	50.8 (40.9–60.9)	931	-	-	51.2 (19.5–82.9)

TRF, traditional risk factor; NRI, net reclassification improvement