Table 3.
Causality scores of 50 patients with liver biopsy performed within 60 days of suspected DILI onset enrolled in the DILIN prospective study
| Total Number | Definite | Highly Likely | Probable | Possible | Unlikely | |
|---|---|---|---|---|---|---|
| Adjudicated DILIN Causality Score | 50 | 17 | 21 | 4 | 5 | 3 |
| Pre-biopsy Consensus Score | 50 | 1 | 17 | 16 | 15 | 1 |
| Post-biopsy Consensus Score | 50 | 8 | 21 | 9 | 5 | 7 |
| Biopsy requested (based on pre-score) | 31 | 0 | 4 | 13 | 13 | 1 |
| Biopsy helpful (based on pre-score) | 35 | 1 | 6 | 16 | 12 | 0 |
| No change in causality score (based on pre-score) after biopsy | 16 | 1 | 10 | 1 | 3 | 1 |
| Change in causality score (based on pre-score) after biopsy | 34 | 0 | 7 | 15 | 12 | 0 |