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. 2022 Apr 19;8:209. doi: 10.1038/s41420-022-01002-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A, B Western blot and its quantification revealed the expression level of NLRP3, C-Caspase-1, GSDMD-N, IL-1β, and IL-18. C Effect of MFG-E8 on H₂O₂-exposed IL-1β production in NP cells was detected by ELISA. D the LDH release in NP cells. E, F Calcein-AM/PI confirmed the death level of H₂O₂-stimulated Rat NP cells. All data are presented as mean ± standard deviation (SD), n = 6; **p < 0.01 vs. untreated group, ^##p < 0.01 vs. H₂O₂ group.