. 2022 Apr 19;12:6436. doi: 10.1038/s41598-022-10477-5

Table 1.

Included studies.

First author, year	Assigned time since CPB cessation (h)	Sample size	AKI Prevalence	TP	FP	FN	TN	pNGAL cut-off (ng/mL)	Sensitivity	Specificity	PPV	NPV	AUROC (95% CI)
Merkle, 2019⁴²	< 4	58	0.36	15	3	6	34	226.98	0.71	0.92	0.83	0.85	0.846 (0.727–0.927)
Merkle, 2019⁴²	24	58	0.36	18	8	3	29	115.87	0.86	0.78	0.69	0.91	0.891 (0.781–0.957)
Introcaso, 2018⁴³	4–8	69	0.35	18	18	6	27	154	0.76	0.59	0.5	0.81	0.71 (0.60–0.82)
Guerci, 2018⁴⁴	4–8	50	0.36	15	5	3	27	112	0.83	0.84	0.75	0.9	0.9 (0.81–0.98)
Schley, 2015⁴⁵	< 4	110	0.34	28	18	9	55	173.43	0.76	0.75	0.609	0.859	0.81 (0.73–0.90)
	4–8	110	0.34	29	18	8	55	178.20	0.78	0.75	0.617	0.873	0.83 (0.75–0.91)
	24	110	0.34	32	18	5	55	137.61	0.86	0.75	0.640	0.916	0.84
Park, 2015⁴⁶	4–8	112	0.12	8	11	5	88	168.5	0.62	0.89	0.421	0.946	0.81 (0.68–0.95)
Kidher, 2014⁴⁷	< 4	53	0.30	13	4	3	33	150	0.80	0.89	0.765	0.917	0.83 (0.70–0.95)
Ghonemy, 2014³⁰	4–8	50	0.34	17	3	0	30	62	0.98	0.92	0.842	0.967	Not stated
Ghonemy, 2014³⁰	< 4	50	0.34	16	2	1	31	62	0.94	0.94	0.888	0.968	Not stated
Parikh, 2011²⁹	< 4	1219	0.05	30	209	30	950	293	0.50	0.82	0.126	0.969	0.7 (SE 0.04)
Perry, 2010⁴⁸	< 4	879	0.09	29	149	46	655	353.5	0.39	0.82	0.163	0.934	0.641 (0.58–0.71)
Perry, 2010⁴⁸	24	879	0.09	42	242	33	562	353.5	0.55	0.70	0.148	0.945	0.670 (0.60–0.74)
Haase, 2009⁴⁹	4–8	100	0.46	34	14	12	40	150.0	0.73	0.74	0.708	0.769	0.77 (0.63–0.91)
Haase-Fielitz, 2009¹⁸	4–8	100	0.23	18	17	5	60	150.0	0.79	0.78	0.52	0.93	0.80 (0.63–0.96)
Haase-Fielitz, 2009¹⁸	24	100	0.23	21	18	2	59	150.0	0.91	0.76	0.53	0.97	0.87 (0.78–0.96)
Perrotti, 2015⁵⁰	24	166	0.31	31	27	21	87	258	0.60	0.76	0.534	0.806	0.7
	12	166	0.31	43	48	9	66	173	0.82	0.58	0.473	0.88	0.7
	4–8	166	0.31	41	48	11	66	155	0.79	0.58	0.461	0.857	0.7
	< 4	166	0.31	28	33	24	81	178	0.54	0.71	0.459	0.771	0.6
Gaipov, 2015⁵¹	12	60	0.67	21	5	19	15	199	0.52	0.73	0.808	0.441	0.649 (0.507–0.774)
Gaipov, 2015⁵¹	24	60	0.67	32	11	8	9	175.4	0.79	0.46	0.744	0.529	0.646 (0.504–0.772)
Prabhu, 2010⁵²	4–8	30	0.27	8	2	0	20	229	1.00	0.91	0.794	1	0.98
Tuladhar, 2009⁵³	< 4	50	0.18	7	14	2	27	426	0.80	0.67	0.333	0.931	0.85 (0.73–0.97)
Othman, 2021²⁸	4–8	25	0.28	7	2	0	16	145	1.00	0.89	0.778	1	0.965