Table 1.
Baseline characteristics of study cohort
| Characteristic | Colorectal cancer (n=41,299) | Matched comparators (n=203,181) |
|---|---|---|
| Female, no. (%) | 19 508 (47.2%) | 95 951 (47.2%) |
| Male, no. (%) | 21 791 (52.8%) | 107 230 (52.8%) |
| Age | ||
| Mean (SD) | 71.8 (11.5) | 71.8 (11.5) |
| Median (IQR) | 72.9 (64.8–80.3) | 72.8 (64.8–80.3) |
| Range, min-max | 18.1–100.0 | 18.3–99.9 |
| Categories, no. (%) | ||
| 18y – <30y | 75 (0.2%) | 337 (0.2%) |
| 30y – <40y | 372 (0.9%) | 1 799 (0.9%) |
| 40y – <50y | 1 452 (3.5%) | 7 084 (3.5%) |
| 50y – <60y | 4 119 (10.0%) | 20 294 (10.0%) |
| 60y – <70y | 10 708 (25.9%) | 52 952 (26.1%) |
| ≥70y | 24 573 (59.5%) | 120 715 (59.4%) |
| Country of birth, no. (%) | ||
| Nordic country | 38 314 (92.8%) | 187 630 (92.3%) |
| Other | 2 985 (7.2%) | 15 549 (7.7%) |
| Missing | 0 | 2 (0.0%) |
| Level of education, no. (%) | ||
| ≤9 years | 15 919 (38.5%) | 77 794 (38.3%) |
| 10–12 years | 15 979 (38.7%) | 77 552 (38.2%) |
| >12 years | 8 961 (21.7%) | 44 752 (22.0%) |
| Missing | 440 (1.1%) | 3 083 (1.5%) |
| Year of colon cancer/Index year, no. (%) | ||
| July 2007–2010 | 16 412 (39.7%) | 80 830 (39.8%) |
| 2011–2013 | 13 746 (33.3%) | 67 637 (33.3%) |
| 2014–2016 | 11 141 (27.0%) | 54 714 (26.9%) |
| Disease history ever before index date, no. (%) | ||
| Cardiovascular disease (CVD) | 22 949 (55.6%) | 94 208 (46.4%) |
| Myocardial infarction (MI) | 3 278 (7.9%) | 16 319 (8.0%) |
| Cardiovascular disease in inpatient care | 20 120 (48.7%) | 78 927 (38.8%) |
| Cancer (excluding CRC) | 13 418 (32.5%) | 41 775 (20.6%) |
| Cancer (excluding CRC) using the Cancer register only | 8 794 (21.3%) | 33 802 (16.6%) |
| Diabetes | 5 516 (13.4%) | 19 427 (9.6%) |
| Neurologic disease | 8 306 (20.1%) | 40 351 (19.9%) |
| None of the above | 11 161 (27.0%) | 77 205 (38.0%) |
| Disease history within 5 years before index date, no. (%) | ||
| Cardiovascular disease (CVD) | 19 031 (46.1%) | 66 229 (32.6%) |
| Myocardial infarction (MI) | 1 450 (3.5%) | 6 244 (3.1%) |
| Cardiovascular disease in inpatient care | 15 941 (38.6%) | 49 553 (24.4%) |
| Cancer (excluding CRC) | 10 026 (24.3%) | 24 237 (11.9%) |
| Cancer (excluding CRC) using the Cancer register only | 3 862 (9.4%) | 12 562 (6.2%) |
| Diabetes | 5 030 (12.2%) | 15 998 (7.9%) |
| Neurologic disease | 4 606 (11.2%) | 21 103 (10.4%) |
| None of the above | 15 824 (38.3%) | 113 770 (56.0%) |
CRC, colorectal cancer.