Table 3.
Baseline characteristics of CRC patients compared to siblings
| Characteristic | Colorectal cancer (n=17,818) | Matched siblings (n=37,610) |
|---|---|---|
| Female, no. (%) | 8 007 (44.9%) | 18 444 (49.0%) |
| Male, no. (%) | 9 811 (55.1%) | 19 166 (51.0%) |
| Age | ||
| Mean (SD) | 65.8 (9.6) | 64.4 (9.8) |
| Median (IQR) | 67.4 (60.7–72.7) | 65.7 (58.8–71.4) |
| Range, min-max | 18.1–84.8 | 18.1–84.5 |
| Categories, no. (%) | ||
| 18y – <30y | 52 (0.3%) | 155 (0.4%) |
| 30y – <40y | 275 (1.5%) | 557 (1.5%) |
| 40y – <50y | 969 (5.4%) | 2 583 (6.9%) |
| 50y – <60y | 2 808 (15.8%) | 7 428 (19.8%) |
| 60y – <70y | 6 994 (39.3%) | 15 285 (40.6%) |
| ≥70y | 6 720 (37.7%) | 11 602 (30.8%) |
| Country of birth, no. (%) | ||
| Nordic country | 17 655 (99.1%) | 37 294 (99.2%) |
| Other | 163 (0.9%) | 315 (0.8%) |
| Missing | 0 | 1 (0.0%) |
| Level of education, no. (%) | ||
| ≤9 years | 5 570 (31.3%) | 12 152 (32.3%) |
| 10–12 years | 7 526 (42.2%) | 16 083 (42.8%) |
| >12 years | 4 671 (26.2%) | 8 841 (23.5%) |
| Missing | 51 (0.3%) | 534 (1.4%) |
| Year of colon cancer/Index year, no. (%) | ||
| July 2007–2010 | 6 121 (34.4%) | 13 329 (35.4%) |
| 2011–2013 | 6 100 (34.2%) | 12 762 (33.9%) |
| 2014–2016 | 5 597 (31.4%) | 11 519 (30.6%) |
| Disease history ever before index date, no. (%) | ||
| Cardiovascular disease (CVD) | 8 227 (46.2%) | 13 845 (36.8%) |
| Myocardial infarction (MI) | 941 (5.3%) | 1 857 (4.9%) |
| Cardiovascular disease in inpatient care | 6 872 (38.6%) | 10 800 (28.7%) |
| Cancer (excluding CRC) | 5 255 (29.5%) | 7 577 (20.1%) |
| Cancer (excluding CRC) using the Cancer register only | 3 289 (18.5%) | 6 541 (17.4%) |
| Diabetes | 2 084 (11.7%) | 2 817 (7.5%) |
| Neurologic disease | 3 513 (19.7%) | 7 568 (20.1%) |
| None of the above | 5 957 (33.4%) | 16 568 (44.1%) |
| Disease history within 5 years before index date, no. (%) | ||
| Cardiovascular disease (CVD) | 6 575 (36.9%) | 8 620 (22.9%) |
| Myocardial infarction (MI) | 399 (2.2%) | 616 (1.6%) |
| Cardiovascular disease in inpatient care | 5 202 (29.2%) | 5 764 (15.3%) |
| Cancer (excluding CRC) | 3 991 (22.4%) | 3 774 (10.0%) |
| Cancer (excluding CRC) using the Cancer register only | 1 475 (8.3%) | 2 144 (5.7%) |
| Diabetes | 1 891 (10.6%) | 2 089 (5.6%) |
| Neurologic disease | 1 891 (10.6%) | 3 304 (8.8%) |
| None of the above | 8 161 (45.8%) | 24 872 (66.1%) |
CRC, colorectal cancer.