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. 2021 Jun 28;16(1):331–337. doi: 10.1007/s12105-021-01353-1

Table 2.

Cases of Endocrine mucin-producing sweat gland carcinoma (EMPSGC) with metastases

Author, year Present case Froehlich et al. (2020) [5] Hadi et al. (2021) [4] Shah et al. (2021) [18]
Age (years)/ sex 78/Male 71/Female 66/Male 60/Male
Primary site Upper eyelid Upper eyelid Upper eyelid Scrotum
Histopathology diagnosis of primary tumor Poorly differentiated carcinoma Unclear Hidradenoma with atypia EMPSGC
Treatment Excision with negative margins Excision Excision with negative margins Excision biopsy, radiotherapy and palliative chemotherapy
Time interval to local recurrences No local recurrence 10 years

First: 7 years

Second: 9 years

Not applicable
Time interval to metastasis from primary diagnosis 9 years 11 years 9 years Synchronous
Sites of metastasis Ipsilateral parotid Ipsilateral parotid Ipsilateral parotid, 8th rib Lymph nodes, pancreas, bone on PET scan
Specimen on which EMPSGC was diagnosed Parotidectomy, with review of histology of primary tumor Incision biopsy of recurrence Parotidectomy, with review of histology of primary tumor Excision biopsy of primary