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. 2022 Mar 21;16(1):1–18. doi: 10.1007/s12105-021-01406-5

Table 1.

2022 5th edition of the World Health Organization (WHO) Classification of Tumours of the nasal cavity, paranasal sinuses, and skull base

Diagnostic Group Category Diagnostic Entity Section
Hamartomas

Respiratory epithelial adenomatoid hamartoma

Seromucinous hamartoma

Nasal chondromesenchymal hamartoma

Respiratory epithelial lesions
Sinonasal papillomas

Sinonasal papilloma, inverted type

Sinonasal papilloma, oncocytic type

Sinonasal papilloma, exophytic type

Carcinomas

Keratinizing squamous cell carcinoma

Non-keratinizing squamous cell carcinoma

NUT carcinoma

SWI/SNF complex-deficient sinonasal carcinoma

Sinonasal lymphoepithelial carcinoma

Sinonasal undifferentiated carcinoma

Teratocarcinosarcoma

HPV-related multiphenotypic sinonasal carcinoma

Adenocarcinoma

Intestinal-type adenocarcinoma of the sinonasal tract

Non-intestinal-type sinonasal adenocarcinoma

Mesenchymal tumors of sinonasal tract

Sinonasal tract angiofibroma

Sinonasal glomangiopericytoma

Biphenotypic sinonasal sarcoma

Chordoma

Other tumors

Sinonasal ameloblastoma

Adamantinomatous craniopharyngioma

Meningioma of sinonasal tract

Olfactory neuroblastoma