Fig. 2.

Basal cell adenoma, membranous pattern in Brooke Spiegler syndrome: Brooke-Spiegler syndrome or familial cylindromatosis is characterized by multiple spiradenomas, cylindromas, spiradenocylindromas and trichoepitheliomas mainly involving the skin of the head and neck as well as a distinctive salivary gland tumour, basal cell adenoma, membranous-type. Sharply delimited islands of basaloid cells are separated by basement membrane material, also seen as small droplets intermixed within tumour islands