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. 2022 Feb 8;47(6):1169–1179. doi: 10.1038/s41386-022-01286-5

Table 3.

Negative social behavior and experience and emotion faces versus neutral faces: significant resultsa.

ROI Experiences of discrimination Reciprocal social impairments
Beta SE T-statistic P value FDR corrected P value R2 Beta SE T-statistic P value FDR corrected P value R2
ACC Left −0.006 0.009 −0.523 0.60 0.64 −0.007 0.111 −0.624 0.53 0.77
Right −0.010 0.010 −0.917 0.36 0.56 −0.005 0.113 −0.481 0.63 0.92
Amg Left −0.003 0.008 −0.329 0.74 0.74 0.016 0.092 1.467 0.14 0.32
Right 0.013 0.008 1.225 0.22 0.53 0.003 0.098 0.302 0.76 0.92
cACC Left −0.007 0.010 −0.696 0.49 0.64 −0.017 0.117 −1.620 0.11 0.32
Right −0.011 0.010 −1.064 0.29 0.53 −0.006 0.116 −0.576 0.56 0.92
FuG Left −0.016 0.008 −1.488 0.14 0.39 −0.035 0.096 −3.240 0.001*** 0.022* 0.041
Right −0.020 0.008 −1.826 0.07 0.24 −0.031 0.094 −2.848 0.004** 0.08
IFG Left −0.015 0.005 −1.435 0.15 0.39 0.026 0.058 2.454 0.014* 0.13
Right −0.025 0.005 −2.369 0.02 0.22 0.021 0.061 1.955 0.05 0.46
ITG Left −0.006 0.006 −0.536 0.59 0.64 −0.012 0.075 −1.143 0.25 0.46
Right −0.005 0.006 −0.510 0.61 0.73 −0.007 0.071 −0.641 0.52 0.92
Ins Left −0.018 0.012 −1.718 0.09 0.39 −0.016 0.145 −1.496 0.13 0.32
Right −0.014 0.012 −1.309 0.19 0.53 −0.011 0.137 −1.068 0.29 0.92
IPL Left −0.030 0.011 −2.763 0.006** 0.05 −0.020 0.132 −1.891 0.06 0.26
Right −0.024 0.011 −2.250 0.024* 0.22 −0.003 0.131 −0.285 0.78 0.92
mOFC Left −0.007 0.003 −0.694 0.49 0.64 −0.006 0.040 −0.536 0.59 0.77
Right −0.004 0.003 −0.398 0.69 0.73 −0.001 0.039 −0.111 0.91 0.96
MTG Left −0.035 0.009 −3.297 0.001*** 0.018* 0.062 −0.014 0.111 −1.316 0.19 0.38
Right −0.022 0.010 −2.096 0.036* 0.22 −0.004 0.113 −0.415 0.68 0.92
NAcc Left −0.006 0.007 −0.557 0.58 0.64 0.004 0.087 0.350 0.73 0.77
Right −0.004 0.007 −0.350 0.73 0.73 −0.008 0.087 −0.752 0.45 0.92
OTG Left −0.016 0.007 −1.503 0.13 0.39 −0.005 0.078 −0.426 0.67 0.77
Right −0.010 0.006 −0.894 0.37 0.56 −0.011 0.075 −1.052 0.29 0.92
PCC Left −0.011 0.011 −1.066 0.29 0.47 −0.011 0.129 −0.989 0.32 0.53
Right −0.008 0.011 −0.727 0.47 0.60 −0.007 0.128 −0.674 0.50 0.92
rACC Left −0.006 0.008 −0.523 0.60 0.64 0.004 0.088 0.346 0.73 0.77
Right −0.009 0.008 −0.805 0.42 0.58 −0.004 0.093 −0.409 0.68 0.92
SFG Left −0.012 0.012 −1.121 0.26 0.47 −0.005 0.140 −0.440 0.66 0.77
Right −0.005 0.012 −0.459 0.65 0.73 0.001 0.140 0.054 0.96 0.96
STG Left −0.014 0.013 −1.279 0.20 0.40 −0.019 0.154 −1.727 0.08 0.30
Right −0.011 0.013 −1.044 0.30 0.53 −0.003 0.148 −0.236 0.81 0.92
TmP Left −0.014 0.004 −1.363 0.17 0.39 0.001 0.052 0.108 0.91 0.91
Right −0.012 0.004 −1.123 0.26 0.53 0.006 0.049 0.564 0.57 0.92
TPJ Left −0.025 0.013 −2.304 0.021* 0.13 −0.021 0.155 −1.977 0.048* 0.26
Right −0.020 0.013 −1.839 0.07 0.24 −0.004 0.153 −0.406 0.68 0.92

SE standard error, FDR false discovery rate, R2 R-squared, ROI region of interest, Amg amygdala, NAcc nucleus accumbens, Ins insula, mOFC medial orbitofrontal cortex, IFG inferior frontal gyrus, cACC caudal anterior cingulate cortex, rACC rostral anterior cingulate cortex, ACC anterior cingulate cortex, OTG occipitotemporal gyrus, IPL inferior parietal lobe, TPJ temporoparietal junction, ITG inferior temporal gyrus, MTG middle temporal gyrus, PCC posterior cingulate cortex, SFG superior frontal gyrus, STG superior temporal gyrus, TmP temporal pole, FuG fusiform gyrus.

Significance codes: *=<0.05; **=<0.01; ***=<0.001.

aNote, FDR-corrections were performed by hemisphere (i.e., 18 FDR-corrections for left ROIs; 18 FDR-corrections for right ROIs.).