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. 2022 Apr 6;9:797135. doi: 10.3389/fmed.2022.797135

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Copyright © 2022 Song, Lai, Lu, Tong and Ran.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of IL-26 exposure on mRNA and protein levels of cytokines, chemokines and adhesion molecules in THP-1 macrophages. (A) Heatmap of 15 immune- or inflammation-related genes. (B) mRNA levels of several cytokines and chemokines in THP-1 macrophages treated with IL-26. (C) Protein levels of several cytokines and chemokines in the supernatants from THP-1 macrophages exposed to IL-26. (D) mRNA and protein levels of ICAM-1 and VCAM-1 in THP-1 macrophages exposed to IL-26. Gene expression results were changed to Data are expressed as mean ± SD and are representative of three independent biological replicates. Images are representative of two independent biological replicates. **P < 0.01, ***P < 0.001.