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. 2022 Apr 6;13:820965. doi: 10.3389/fimmu.2022.820965

Table 3.

QTLs surpassing the significance threshold (P < 5 × 10-7) for evidence of an association with tolerance.

BTA1 QTL start (bp) QTL end (bp) P-value most significant SNP SNP position 2 SNP ID Annotation Genes in QTL 3 N° ofsignificant SNPs in QTL
16 21307714 22307714 1,58E-07 21807714 SPATA17, RRP15, TGFB2, U6 1
9 100997090 101997090 1,60E-07 101497090 rs436366135 Intron TBXT,U6, SFT2D1, MPC1, RPS6KA2, RNASET2, CEP43, CCR6, GPR31, U4, TTLL2, UNC93A, ENSBTAG0000051317, ENSBTAG00000050267, ENSBTAG00000054087, ENSBTAG00000053924 1
4 66265303 67309158 2,55E-07 66765303 rs382143408 Intron PLEKHA8, SCRN1, FKBP14, WIPF3, PRR15, CHN2, CPVL, TRIL, CREB5, ENSBTAG00000054573 8
26 20050339 21059555 2,92E-07 20559555 rs381461650 Intergenic CNNM1, GOT1, U6, NKX2-3, SLC25A28, ENTPD7, COX15, CUTC, ABCC2, DNMBP, CPN1, ERLIN1, CHUK, ENSBTAG00000052639, ENSBTAG00000050951, ENSBTAG00000045082, ENSBTAG00000044887, ENSBTAG00000033021, ENSBTAG00000023939 2
16 71510469 72510469 3,61E-07 72010469 rs210839825 Intron DTL, INTS7, LPGAT1, NEK2, SLC30A1, RD3, TRAF5, RCOR3, KCNH1, ENSBTAG00000048992, ENSBTAG00000048697, ENSBTAG00000050969, ENSBTAG00000053608 1
26 33908564 34908564 3,69E-07 34408564 rs210720477 Intergenic HABP2, NRAP, CASP7, PLEKHS1, NHLRC2, DCLRE1A, ADRB1, CCDC186, TDRD1, VWA2, AFAP1L2, bta-mir2285dg, ABLIM1, ENSBTAG00000051735, ENSBTAG00000053724 1
25 11894597 12930197 3,81E-07 12394597 rs109954622 Intergenic ERCC4 12
25 8908535 9991143 3,93E-07 9408535 rs380720091 Intron U6, ATF7IP6, EMP2, TEKT5, NUBP1, TVP23A, CIITA, DEXI, CLEC16A, SOCS1, RMI2, TNP2, PRM1, PRM2, PRM3, ENSBTAG00000052111 13
4 80073101 81073101 4,02E-07 80573101 rs379792050 Intron SUGCT, MPLKIP, CDK13, ENSBTAG00000049322 1

1QTL location, 2SNP location in the genome, 3Candidate genes located within the identified QTL.