Table 2.

Biomarkers for checkpoint inhibitors

Biomarker	Tumor Type	Definition
Tumor Proportion Score	NSCLC	Percentage of tumor cells expressing the protein PD-L1 relative to the total number of tumor cells
Combined Proportion Score	UC H&NSCC	Percentage of PD-L1 expression in tumor and infiltrating immune cells relative to the total number of tumor cells
MSI-H	Tumor Agnostic	Microsatellite Instability

PD-L1: programmed dead ligand-1; NSCLC: non small-cell lung cancer; H&NSCC: head and neck squamous cell carcinoma; UC: urothelial carcinoma