Domain composition of PABPC1(14) and Paip2A(17). PABPC1 is a 636-residue protein with four RNA recognition motifs (RRMs) in the N terminus. Residues 11 to 89, 99 to 175, 191 to 268, and 294 to 370 are RRM1, RRM2, RRM3, and RRM4, respectively. The C terminus contains an unstructured region named as the linker and a PABC (PABP C-terminal domain). Paip2A is a 127-residue protein with PABP-interacting motif 1 (PAM1) in the N terminus and PABP-interacting motif 2 (PAM2) in the C terminus. PABPC1, poly(A)-binding protein C1; Paip2A, PABP-interacting protein 2A.