Table 1.
Top 30 genes upregulated in CD44-high/CD24-low cluster (Cluster 11). The genes were obtained using the Finallmarkers function from the Seurat package with expression threshold set at 0.25.
| Gene | P value |
|---|---|
| Pcdh7 | 1.09E-150 |
| Dcn | 5.55E-119 |
| Plpp3 | 3.19E-106 |
| Creb3l1 | 3.22E-104 |
| Hexa | 7.26E-94 |
| Ppic | 4.18E-87 |
| Serpina3n | 2.91E-85 |
| Mmp14 | 9.55E-80 |
| Snhg18 | 1.01E-75 |
| Vcan | 1.97E-75 |
| Ifitm2 | 3.08E-74 |
| Col4a1 | 1.59E-73 |
| Gstm2 | 8.51E-65 |
| Serf2 | 5.42E-60 |
| Calu | 1.40E-54 |
| Marcks | 2.86E-51 |
| Bmp1 | 7.37E-50 |
| Selenof | 2.12E-49 |
| Itm2c | 1.42E-41 |
| Rrbp1 | 2.50E-40 |
| Vasn | 3.81E-38 |
| Col27a1 | 1.73E-37 |
| Ugdh | 2.18E-37 |
| Il6st | 1.15E-31 |
| Ckap4 | 3.62E-30 |
| Vat1 | 4.21E-30 |
| Lamc1 | 9.67E-30 |
| Pdia3 | 6.54E-26 |
| Cyth3 | 8.66E-19 |
Pcdh7: Protocadherin-7; Dcn: decorin; Plpp3: phospholipid phosphatase 3; Creb3l1: CAMP responsive element binding protein 3 like 1; Hexa: hexosaminidase A; Ppic: peptidylprolyl isomerase C; Serpina3n: serine protease inhibitor A3N precursor; Mmp14-matrix metallopeptidase 14; Snhg18: small nucleolar RNA host Gene 18; Vcan: versican; Ifitm2: interferon induced transmembrane protein 2; Col4a1: collagen alpha-1(IV); Gstm2: glutathione S-transferase mu 2; Serf2: small EDRK-rich factor 2; Calu: calumenin; Marcks: myristoylated alanine rich protein kinase C substrate; Bmp-1 Bone morphogenetic protein-1; Selenof: selenoprotein F precursor; Itm2c: integral membrane protein 2C; Rrbp1: ribosome-binding protein 1; Vasn: vasorin; col27a1: collagen alpha-1 (XXVII); Ugdh: UDP-glucose dehydrogenase; Il6st: interleukin 6 signal transducer; Ckap4: cytoskeleton associated protein 4; Vat1: vesicle amine transport 1; Lamc1: laminin subunit gamma-1; Pdia3: protein disulfide-isomerase A3; Cyth3: cytohesin-3