Table 2.

Effect of time and unit on the number of isolated multidrug-resistant organisms in hospital-acquired infections from 2015 to 2020.

Effect	Wilk's lambda	p value	Effect size (squared Eta)	Interpretation
Time (year)	0.311	0.008∗	0.689	The effect of time explained 68.9% of the variability in the number of isolated MDRs in HAI
Unit	-	0.071	0.189	The effect of the unit alone was not significant to explain the variability in the number of isolated MDRs in HAI
Time∗unit	0.409	0.036∗	0.591	The effect of the time∗unit explained 59.1% of the variability in the number of isolated MDRs in HAI

MDR: multidrug-resistant; HAI: hospital-acquired infections; Multifactorial Repeated-Measure ANOVA analyzing the effect of time (year) and unit (intensive care unit versus long-term care) on the change in the raw number of multidrug-resistant organisms isolated in hospital-acquired infections, from the start of the antimicrobial stewardship program in 2015 to 2020. The yearly estimated marginal means are depicted by the unit in Figure 6. Squared Eta >0.14 indicates a large effect. ^∗Statistically significant result (p < 0.05).