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rpoB mutations observed in rifampin-resistant mutants
| Mutation | Codon change | No. (%) of mutations |
|---|---|---|
| S531L | TCG→ TTG | 39 (60.9) |
| H526Y | CAC→ TAC | 6 (9.4) |
| H526R | CAC→ CGC | 5 (7.8) |
| H526D | CAC→ GAC | 4 (6.2) |
| S522L | TCG→ TTG | 4 (6.2) |
| S531W | TCG→ TGG | 2 (3.1) |
| H526P | CAC→ CCC | 1 (1.6) |
| D516V | GAC→ GTC | 1 (1.6) |
| Deletion | GAC, codon 516a | 1 (1.6) |
| Insertion | TTC, after codon 513 (Q) | 1 (1.6) |
| Total | 64 |
Mutation not previously reported.
