Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Percentage of oca2 mosaic individuals induced by CRISPR/Cas9 in G0s.
| target | injected | survived | survival (%) | mutant | mosaic frequency (%) |
|---|---|---|---|---|---|
| #1 oca2 exon 1 & 3 | 36 | 17 | 47 | 17 | 100 |
| #2 oca2 exon 1 | 35 | 7 | 20 | 4 | 57 |
| #3 oca2 exon 1 | 53 | 11 | 21 | 2 | 18 |
| #4 oca2 exon 1 | 25 | 9 | 36 | 4 | 44 |
| #5 oca2 exon 1 | 55 | 15 | 27 | 6 | 40 |
| #6 oca2 exon 1 | 20 | 4 | 20 | 4 | 100 |
| average survival | 28.5 | average mosaicism | 60 | ||
