Skip to main content
. Author manuscript; available in PMC: 2022 Apr 20.
Published in final edited form as: Reprod Sci. 2008 Nov;15(9):878–894. doi: 10.1177/1933719108324171

Figure 10.

Figure 10.

2-Methoxyestradiol (2ME) in combination with TRAIL induces apoptosis in cancerous and benign tumor cells but not in normal cultured human cells of ovarian origin. MTS cell cytotoxicity assays after 2ME (5 μM) addition for 48 hours in cultured normal ovary, benign tumor, and ovarian cancer cells. Data represent percentage in respect to control. Standard derivation of the means is shown, each consisting of 5 replicates. Statistical significance in respect to vehicle treated control (★) and in respect to 2ME or TRAIL treatment (#) for each cell type was set at P < .05 using the Mann-Whitney test.