Flow cytometry analysis of 2-methoxyestradiol (2ME) and TRAIL-mediated apoptosis in A2780-wt (vector) and A2780/Bcl-XL cells. Representative flow cytometry analysis of A2780-wt (left side) and A2780/Bcl-XL cells (right side), demonstrating each phase of the cell cycle (GO/G1 = M2, S = M3, G2/M = M4) and an apoptotic sub-GO/G1 peak (M1), after treatment with ethanol vehicle (Control), TRAIL 200 ng/mL for 18 hours, 2ME (5 μM) for 48 hours or 2ME for 48 hours with TRAIL addition occurring 18 hours before the end of the experiment (2ME + TRAIL).