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Berberine improved cardiac function in LPS-induced septic mice, but it was inhibited by L-NAME. (A) Representative M-mode images. Changes of (B) LVEF, (C) LVFS and (D) HR. Results are means ± SEM. *P<0.05 and **P<0.01 were considered significant. LPS, lipopolysaccharide; L-NAME, Nω-nitro-L-arginine methyl ester; LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; HR, heart rate.
