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Berberine alleviated cardiac injury in LPS-induced septic mice, but it was inhibited by L-NAME. (A) LDH, (B) CK, (C) CK-MB, (D) TNF-α and (E) IL-1β levels in the plasma. Results are means ± SEM. *P<0.05 and **P<0.01 were considered significant. LPS, lipopolysaccharide; L-NAME, Nω-nitro-L-arginine methyl ester; LDH, lactate dehydrogenase; CK, Creatine kinase; CK-MB, Creatine kinase-MB.
