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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: J Physiol. 2022 Mar 6;600(8):1913–1932. doi: 10.1113/JP282237

Figure 4.

Figure 4.

Measured versus model-predicted LAD flow for each of four experimental animals under three different experimental conditions. In control and hemodilution conditions, coronary autoregulation impedes a significant increase in flow with increases in CPP (60–120 mmHg). However, the overall myocardial blood flow is elevated with hemodilution. Dobutamine infusion significantly increases the flow compared to the control and hemodilution conditions and largely abolishes the autoregulatory response in all animals.