TABLE 1.
Baseline Characteristics of Participants Included in the Study
| HIV+ (N = 5,747) | HIV− (N = 33,497) | ||||
|---|---|---|---|---|---|
| N | %/Mean ± SD | N | %/Mean ± SD | STD | |
| Age (yrs) | 5,747 | 58.3 ± 9.8 | 33,463 | 70.1 ± 12.0 | −1.07 |
| Male | 5,747 | 98.0 | 33,497 | 97.6 | −0.05 |
| White | 5,747 | 34.4 | 33,497 | 67.7 | 0.77 |
| Black | 5,747 | 56.4 | 33,497 | 23.7 | |
| Smoker | 5,747 | 51.9 | 33,497 | 32.1 | 0.41 |
| Systolic BP (mm Hg) | 4,417 | 135 ± 25 | 25,778 | 136 ± 24 | −0.04 |
| Diastolic BP (mm Hg) | 4,407 | 80 ± 16 | 25,769 | 75 ± 15 | 0.31 |
| BMI (kg/m2) | 3,303 | 26.6 ± 6.7 | 19,892 | 29.7 ± 7.3 | −0.44 |
| Glucose (mg/dl) | 5,299 | 119 ± 46 | 30,020 | 126 ± 48 | −0.15 |
| LDL-c (mg/dl) | 5,133 | 90 ± 37 | 28,906 | 90 ± 36 | 0.00 |
| HDL-c (mg/dl) | 5,142 | 42 ± 15 | 28,952 | 43 ± 14 | −0.10 |
| Triglycerides (mg/dl) | 5,157 | 163 ±107 | 29,084 | 139 ± 90 | 0.25 |
| BNP (pg/ml) | 2,971 | 765 ± 1,305 | 14,836 | 639 ± 1,169 | 0.00 |
| Ejection fraction (%) | 4,611 | 45 ± 16 | 23,918 | 45 ± 16 | −0.04 |
| Creatinine (mg/dl) | 5,284 | 1.9 ± 2.2 | 29,908 | 1.5 ± 1.2 | 0.25 |
| Hemoglobin (mg/dl) | 5,263 | 12.6 ± 2.3 | 29,453 | 13.0 ± 2.2 | −0.18 |
| Albumin (mg/dl) | 5,265 | 3.5 ± 0.7 | 29,362 | 3.7 ± 0.7 | −0.28 |
| WBC count (cells/μl) | 5,249 | 6.8 ± 3.5 | 29,440 | 8.2 ± 6.4 | −0.28 |
| ALT (U/l) | 5,282 | 35 ± 30 | 29,764 | 28 ± 23 | 0.28 |
| Elixhauser index | 5,747 | 5.10 ± 3.17 | 33,497 | 2.95 ± 2.62 | 0.74 |
| Hypertension | 5,747 | 75.2 | 33,497 | 77.2 | −0.05 |
| DM (no complication) | 5,747 | 30.9 | 33,497 | 37.0 | −0.13 |
| DM (with complication) | 5,747 | 15.2 | 33,497 | 17.8 | −0.07 |
| MI | 5,747 | 20.2 | 33,497 | 22.9 | −0.07 |
| PVD | 5,747 | 12.0 | 33,497 | 17.5 | −0.16 |
| CLD | 5,747 | 33.0 | 33,497 | 28.0 | 0.11 |
| Renal failure | 5,747 | 13.8 | 33,497 | 7.3 | 0.21 |
| Liver failure | 5,747 | 28.7 | 33,497 | 5.7 | 0.64 |
| Obesity | 5,747 | 14.8 | 33,497 | 23.3 | −0.22 |
| Alcohol abuse | 5,747 | 31.7 | 33,497 | 12.7 | 0.47 |
| Drug abuse | 5,747 | 36.6 | 33,497 | 8.3 | 0.72 |
| Depression | 5,747 | 41.2 | 33,497 | 22.9 | 0.40 |
| Beta-blocker | 5,747 | 58.3 | 33,497 | 59.8 | −0.03 |
| ACEI/ARB | 5,747 | 59.3 | 33,497 | 57.8 | −0.04 |
| MRA | 5,747 | 13.5 | 33,497 | 11.8 | 0.05 |
p < 0.05 for all except BNP.
ACEI/ARB = angiotensin-converting enzyme inhibitor/angiotensin receptor blocker; ALT = aspartate transaminase; BMI = body mass index; BNP = brain natriuretic peptide; BP = blood pressure; CLD = chronic lung disease; DM = diabetes; HDL-c = high-density lipoprotein cholesterol; LDL-c = low-density lipoprotein cholesterol; MI = myocardial infarction; MRA = mineralocorticoid receptor antagonist; PVD = peripheral vascular disease; STD = standard difference; WBC = white blood cell.