FIGURE 7.

BCD facilitates nuclear translocation of Nrf2 in TWP-induced POI mice ovaries. Western blot experiments on Nrf2/Keap 1 pathway proteins were carried out. The relative protein concentrations were visualized with the ImageJ 6.0 software program. Relative quantities of Bach 1 localized in cytoplasm (A) and in nucleus (B). The relative intensities of Nrf2 localized in cytoplasm (C) and in nucleus (D). The total content of Bach 1 (E), and the nuclear translocation rate of Bach 1 (F). The total content of Nrf2 (G), and the nuclear translocation rate of Nrf2 (H). The relative intensities of Keap 1 (I) and HO-1 (J). All data is a combination of eight mice from each group. The data is visualized in terms of means ± SEM. (*p < 0.05, **p < 0.01, compared with the Blank group; ^# p < 0.05, ^## p < 0.01, compared with the Model group).