Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Tepotinib restrains activation of MET and PI3K/AKT signaling pathways in melanoma cells. The expression levels of p-MET, MET, p-PI3K, PI3K, p-AKT and AKT in WM451 cells treated with or without 10 ng/ml tepotinib were determined using western blot analysis. *P<0.05, **P<0.01 and ***P<0.001 vs. control (DMSO) group. MET, MET proto-oncogene, receptor tyrosine kinase; p-, phosphorylated.
