Grant 1995.

Methods	Cross‐over study: participants observed for two consecutive six month periods.
Participants	86 children (described as having asthma) 2 to 14 years of age who had made 2 or more unscheduled outpatient (emergency department or primary‐care clinic) visits in the preceding year. Mean age and gender balance was unclear.
Interventions	A single 2mg per Kg dose of prednisolone.
Outcomes	Unscheduled medical review.
Notes	An intention to treat analysis was not conducted. The primary analysis comprised a paired T‐test in which each participant who completed the 12 month trial was compared with his or herself (6 month period with prednisolone vs. 6 month period with placebo). The reported data did not facilitate raw data extraction and the authors were unable to provide clarifications. Data restricted to episodes af wheeze that resulted in treatment with the study medication were not available.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	Study investigators unaware as to order of treatment group assignment