Fig. 2.

TAZ alone does not induce cancer. A Schematic illustration of the experimental procedure. Transposons encoding TAZ^S89A were mixed with plasmids expressing the Sleeping Beauty transposase, and injected via hydrodynamic tail vein injection. B Gross morphology of representative livers expressing TAZ^S89A and enhanced green fluorescent protein (EGFP, a control). Livers were harvested at 16 weeks following the hydrodynamic injection (n = 5). C Microscopic images showing H&E and IHC staining for pan CK, SOX9, and Ki-67 in sections of livers shown in (B). Scale bar, 50 μm