Table 2.

NRG1 expressions in the aganglionic colon of patients with HSCR and control colons

NRG1 isoform	HSCR (ΔCT ± SD)	Control (ΔCT ± SD)	ΔΔCT (95% CI)	Fold change	p-value
Type I	14.47 ± 1.66	17.42 ± 1.51	-2.95(-4.23-(-1.67))	7.7*	< 0.01
Type II	14.61 ± 2.43	16.29 ± 2.19	-1.69 (-3.56–0.18)	3.2	0.07
Type III	15.30 ± 2.80	16.32 ± 2.58	-1.02 (-3.47–1.44)	2.0	0.40
HRGβ1/HRGβ2	13.62 ± 3.42	14.75 ± 1.26	-1.13 (-3.75–1.48)	3.3*	0.01
HRGβ3	4.01 ± 0.94	4.88 ± 1.47	-0.87 (-1.77–0.03)	1.5	0.06
HRGα/NDF43	13.19 ± 3.97	13.50 ± 2.72	-0.31 (-3.29–2.68)	1.2	0.83
NDF43	16.53 ± 2.93	18.52 ± 1.14	-1.99 (-4.15–0.16)	3.9	0.07

^*p-value < 0.05