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. 2022 Apr 19;22:340. doi: 10.1186/s12884-022-04678-z

Table 3.

Differences in NTD-related stillbirth and infant mortality with late ToPFA cases, Turkey, 2014–2019, (n = 3911)

Variables Overall Stillbirth and infant death ToPFA p
n 3911 3440 471
Gender (%) 0.160
 Female 62.9 63.0 62.2
 Male 36.7 36.7 36.9
 Unknown 0.4 0.3 0.8
Gestational age (week) 32.6 ± 5.8 33.7 ± 5.1 24.5 ± 3.4 < 0.001
Birthweight (gr) 1736 ± 996 1875 ± 971 731 ± 445 < 0.001
Maternal age (year) 28.5 ± 6.5 28.6 ± 6.5 27.9 ± 6.4 0.033
Maternal education (year) 5.6 ± 4.4 5.4 ± 4.3 8.1 ± 4.3 < 0.001
Paternal education (year) 6.9 ± 4.4 6.7 ± 4.4 8.5 ± 4.3 < 0.001
Household size 4.6 ± 2.7 4.7 ± 2.7 3.7 ± 1.9 < 0.001
Consanguineous marriage (%) < 0.001
 Yes 22.8 24.6a 9.8b
 No 71.4 69.5a 85.6b
 Unknown 5.8 5.9a 4.7a
Miscarriage/stillbirth history (%) 0.002
 Yes 30.1 31.0a 23.8b
 No 64.8 63.8a 72.0b
 Unknown 5.1 5.2a 4.2a
Maternal smoking (%) 0.674
 Yes 6.3 6.2 7.2
 No 85.6 85.6 85.1
 Unknown 8.1 8.1 7.6
Pregnancy type (%) 0.118
 Normal 94.1 93.8 96.2
 Assisted reproductive technology 2.2 2.3 1.3
 Unknown 3.7 3.9 2.5
Parity(%) 0.006
 Nullipar 24.2 23.4a 30.1b
 Multipar 72.1 72.8a 66.7b
 Unknown 3.7 3.7a 3.2a
Number of antenatal care 5.9 ± 5.0 6.0 ± 5.1 5.7 ± 4.7  0.341
Number of fetuses in the pregnancy (%) < 0.001
 Singleton 91.9 91.3a 96.4b
 Twin/triplet 4.2 4.6a 1.1b
 Unknown 3.9 4.1a 2.5a
Delivery type (%) < 0.001
 Vaginal delivery 44.3 39.4a 80.3b
 Cesarean section 50.8 55.7a 15.3b
 Unknown 4.9 5.0a 4.5a
Regions (%) < 0.001
 West 27.5 24.7a 47.8b
 South 10.0 10.3a 7.9a
 Central 12.1 10.7a 22.3b
 North 4.0 3.3a 9.8b
 East 46.4 51.0a 12.3b

NTD Neural tube defect, ToPFA Termination of pregnancy for fetal anomaly

Values are column percentage or mean ± SD

a,bDifferent letters in the same row are significant