Table 3.

Sensitivity analysis for primary outcome total and by treatment allocation*

		Total (N = 53)		Estradiol Arm (N = 30)		Placebo Arm (N = 23)		Mean difference Estrogen-placebo (90% CI)
VuAS (range 0–3)	6 weeks	51	0.78 (0.80)	28	0.75 (0.80)	23	0.81 (0.83)	-0.06 (-0.44 to 0.32)
	12 weeks	51	0.14 (0.24)	28	0.10 (0.25)	23	0.18 (0.23)	-0.09 (-0.20 to 0.03)
	6 months	48	0.13 (0.24)	27	0.15 (0.27)	21	0.10 (0.21)	0.05 (-0.07 to 0.17)

Values expressed as N, mean (SD)

VuAS = Vulvar Assessment Scale

*Excludes six treatment non-adherent patients; accounts for missing data in adherent patients