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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Cancer. 2021 May 27;127(17):3137–3144. doi: 10.1002/cncr.33639

TABLE 1.

Current Opioid Prescribing Laws and Cancer Exemptions by State

State Law Date Enacted Description Cancer Exemption Description of Exemption
Alabama No
Alaska HB 159 07/2017 7-d limit for initial prescription for outpatient use Yes Does not apply to pain associated with cancer
Arizona SB 1001a 01/2018 5-d limit for initial prescription; 14-d limit following surgical procedure; 90 MME/d limit for any new prescription Yes Lias an active oncology diagnosis
Arkansas No
California No
Colorado SB 18–22 05/2018 7-d limit for initial prescription if the patient has not received an opioid prescription by that prescriber in the last 12 mo Yes Does not apply to patients diagnosed with cancer and experiencing cancer-related pain
Connecticut HB 7052 06/2017 7-d limit for initial prescription for outpatient use Yes Does not apply to pain associated with a cancer diagnosis
Delaware Delaware Administrative Code CSA9.0 04/2016 7-d limit for initial prescription for an acute pain episode, outpatient use Yes Active cancer treatment patients or patients experiencing cancer-related pain
Florida HB 21 03/2018 3-d limit for prescriptions for acute pain; on the basis of the provider’s judgment, prescription can be increased to a 7-d limit Yes Does not apply to pain related to cancer
Georgia No
Hawaii SB 505 07/2017 7-d limit for initial concurrent prescriptions of opioids and benzodiazepines Yes Does not include treatment for cancer
Idaho No
Illinois No
Indiana SB 226 03/2017 7-d limit for an initial prescription Yes Does not include treatment for cancer
Iowa No
Kansas No
Kentucky HB 333 04/2017 3-d prescription limit for a Schedule III controlled substance for acute pain Yes Does not apply to pain associated with a valid cancer diagnosis
Louisiana HB 192 08/2017 7-d limit for initial prescription for acute pain for outpatient use Yes Does not apply to pain associated with a cancer diagnosis
Maine PL 488 03/2017 7-d limit and 100 MME/d for prescriptions for acute pain; 30-d limit and 100 MME/d for prescriptions for chronic pain Yes Does not apply to pain associated with active and aftercare cancer treatment
Maryland HB 1432 05/2017 7-d limit for initial prescription for the treatment of pain Yes Does not apply to pain associated with a cancer diagnosis
Massachusetts HB 4056 03/2016 7-d limit for initial prescription for outpatient use Yes Does not apply to pain associated with a cancer diagnosis
Michigan PA 251 07/2018 7-d limit for acute pain within a 7-d period No
Minnesota Minnesota Statute 152.11 07/2019 7-d prescription limit for acute pain; 4-d prescription limitation for dental pain or surgery and refractive surgery Yes Does not include pain being treated as part of cancer care
Mississippi Mississippi Code 73–43–11 10/2018 Requires prescription for lowest effective dosage and suggested minimum of 50 MME/d and maximum of 90 MME/d; 3-d limitation encouraged and maximum of 10-d supply for acute pain; long-acting opioids are prohibited for acute pain Yes Does not apply to acute noncancer/nonterminal pain
Missouri SB 826 07/2018 7-d limit for initial prescriptions for acute pain; dentists must document and explain prescriptions of extended-release opioids or doses greater than 50 MMEs for the treatment of acute pain Yes Does not apply to pain being treated as a part of cancer care or to a patient who is currently undergoing treatment for cancer
Montana HB 86 03/2019 7-d limit for an opioid-naive patient Yes Does not apply to pain associated with cancer
Nebraska Legislative Bill 931 04/2018 Recommended to treat acute pain with non-opiate or nonpharmacological options; short-term use of opiates may be appropriate for more severe pain or acute injury; if a patient needs medication beyond 3 d, the prescriber should reevaluate the patient before issuing another prescription for opiates Yes Does not apply to the treatment of pain associated with a cancer diagnosis
Nevada AB 474 06/2017 14-d limit for initial prescription of Schedule II-IV controlled substances for acute pain; maximum of 90 MMEs for opioid that has never been issued to patient before or has been issued more than 19 d before the prescription No
New Hampshire No
New Jersey SB 3 02/2017 5-d limit for initial prescription for acute pain and lowest effective dose of opioid for any prescription for acute pain Yes Does not apply to pain being treated as a part of cancer care or to a patient who is currently undergoing active treatment for cancer
New Mexico No
New York SB 8139 07/2016 7-d limit for initial prescription for acute pain Yes Does not apply to pain being treated as a part of cancer care
North Carolina HB 243 06/2017 5-d limit for initial prescription for acute pain; 7-d limit for prescription for postoperative relief Yes Does not apply to pain being treated as a part of cancer care
North Dakota No
Ohio Administrative Code 4731–11–13 08/2017 7-d limit and MME cannot exceed an average of 30 MME/d for prescription for acute pain; may be exceeded if the pain is expected to persist for longer than 7 d on the basis of the pathology causing this pain Yes Does not apply to a patient with cancer or another condition associated with the patient’s cancer or history of cancer
Oklahoma SB 1446 05/2018 7-d initial prescription limit for acute pain Yes Does not apply to a patient undergoing active treatment for cancer
Oregon No
Pennsylvania Act 122 11/2016 7-d limit for prescriptions for an individual seeking treatment in an emergency department or urgent care center, or who is in observation status in a hospital Yes Does not apply to the treatment of pain associated with a cancer diagnosis
Rhode Island SB 2823 03/2016 7-d limit for initial prescription; 30 MME/d for a maximum of 20 doses for initial prescriptions for acute pain Yes Does not apply to pain associated with a cancer diagnosis
South Carolina HB 918 05/2018 7-d limit and 90 MME/d for initial prescriptions for acute pain or postoperative pain to the lowest effective dose Yes Does not apply to pain being treated as a part of cancer care
South Dakota No
Tennessee PC 1039 05/2018 3-d/180-MME limit for initial prescription and initial fill of higher dosages and durations limited to half of the total prescribed amounts; 10- or 30-d limitation for medically necessary prescriptions (maximum 1200 cumulative MMEs) Yes Does not apply to the treatment of patients with malignant pain who are undergoing active or palliative cancer treatment or who are receiving hospice care
Texas HB 2174 09/2019 10-d limit for opioid prescriptions for acute pain with no refills Yes Does not apply to pain being treated as a part of cancer care
Utah HB 50 03/2017 7-d limit for Schedule II or III opioids for acute pain No
Vermont Rule Governing the Prescribingof Opioids for Pain pursuant to Act 173 2a 06/2016 For patients who are opioid naïve and are receiving their first prescriptions not administered in a healthcare setting, the following limitations apply: up to 3-d limit and 72 MME/d or 5-d and 120 MME/d for moderate pain; 3-d limit and 96 MME/d or 5-d limit and 160 MME/d for severe pain; 7-d limit and 350 MME/d for extreme pain No
Virginia Regulations Governing Opioid Prescribing for Pain and Prescribing of Buprenorphine for Addiction Treatment, 18 VAC 85–21–10 et seq. 04/2017 7-d limit for prescription for acute nonoperative pain; documentation of the reasons to exceed 50 MME/d; before exceeding 120 MME/d, the prescriber shall document in the medical record the reasonable justification for such doses or refer to or consult with a pain management specialist; naloxone shall be prescribed for any patient when risk factors of prior overdose, substance abuse, doses in excess of 120 MME/d, or concomitant benzodiazepine are present Does not apply to the treatment of acute or chronic pain related to cancer
Washington HB 1427 01/2019 3-d prescription limit recommended for acute, nonoperative pain; documentation required for more than a 7-d supply; 14-d prescription limit for subacute pain Does not apply to the treatment of patients with cancer-related pain
West Virginia SB 273 06/2018 Lowest effective dose for an initial prescription; 3-d limit for prescriptions written by a dentist or optometrist; 4-d prescription limit for outpatient use for care in the emergency room or urgent care; 7-d prescription limit for other practitioners Yes Does not apply to patients with cancer
Wisconsin No
Wyoming SF 00046 07/2019 7-d limit for an opioid-naive patient Yes Does not apply to cancer treatment

Abbreviations: HB, House Bill; MME, morphine milligram equivalent; CSA, Controlled Substances Act; PA, Public Act; PC, Public Chapter; PL, Public Law; SB, Senate Bill; SF, Senate File; VAC, Virginia Administrative Code.

Note: States that defer to Medical Boards and/or administrative bodies are not included if it is unclear whether prescribing regulations carry the force of law.