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. 2022 Apr 19;5(4):e227970. doi: 10.1001/jamanetworkopen.2022.7970

Figure. Timeline of the Drugs Used During the COVID-19 Pandemic.

Figure.

ABC-110 indicates Study of Opaganib in Coronavirus Disease 2019 Pneumonia (COVID-19); ACE-ID-201, A Phase 2, Open Label, Randomized Study of the Efficacy and Safety of Acalabrutinib with Best Supportive Care Vs Best Supportive Care in Subjects Hospitalized with COVID-19; AMMURAVID, Factorial Randomized Trial of Remdesivir and Baricitinib Plus Dexamethasone for COVID-19; ColCOVID, Colchicine Counteracting Inflammation in COVID-19 Pneumonia; COMBAT-19, Mavrilimumab in Severe COVID-19 Pneumonia and Hyper-inflammation; COV-BARRIER, Study of Baricitinib (LY3009104) in Children With COVID-19; COVER, COVID Ivermectin - Randomized, Double-blind, Multi Centre Phase II, Proof of Concept, Dose Finding Clinical Trial on Ivermectin for the Early Treatment of COVID-19; DEF-IVID19, Defibrotide in COVID-19 Pneumonia - Use of Defibrotide to Reduce Progression of Acute Respiratory Failure Rate in Patients With COVID-19 Pneumonia; FibroCov, Open-label, Randomized, Parallel-arm Study Investigating the Efficacy and Safety of Intravenous Administration of Pamrevlumab Vs Standard of Care in Patients With COVID-19; HS216C17, Clinical Study to Evaluate the Performance and Safety of Favipiravir in COVID-19; IVIG/H/COVID-19, High Dose Intravenous Polyvalent Immunoglobulin (IVIG) in Patients With Early Inflammatory COVID-19; RANCONA, A Randomized Clinical Trial of Nafamostat: A Potent Transmembrane Protease Serine 2 (TMPRSS2) Inhibitor for the Treatment of Covid-19; REPAVID-19, Reparixin in COVID-19 Pneumonia - Efficacy and Safety; SOBI.IMMUNO-101, Efficacy and Safety of Emapalumab and Anakinra in Reducing Hyperinflammation and Respiratory Distress in Patients With COVID-19 Infection; SOLIDARITY, Efficacy of Different Anti-viral Drugs in COVID 19 Infected Patients; STAUNCH, Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection; TOGETHER, Trial to Evaluate the Effect of Peginterferon Lambda for the Treatment of COVID-19; XPORT-CoV-1001, Evaluation of Activity and Safety of Oral Selinexor in Participants With Severe COVID-19 Infection.