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α1-adrenergic contractions in small mesenteric arteries. Phenylephrine (PHE; 0.01–30 μmol/L)-induced contractions of stretched 2nd-order mesenteric arteries isolated from NT (A) and dnTrx-Tg (B) mice fed a normal chow (NC) diet (circles), high fat/high sucrose (HFS) diet (squares), and HFS followed by tail vein injection of the ONOO− decomposition compound FeTMPyP (triangles). Values are shown as means ± SEM. *p < .05 versus NC. Number of mice (n = 5, males and females)
