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. 2022 Apr 20;12(19):12011–12052. doi: 10.1039/d2ra00067a

α-Glucosidase inhibitory activity of divalent metal complexes bearing Schiff base ligands.

Entry Compounds Structure number Yeast enzyme rat intestinal enzyme Ref.
IC50 (μM) IC50 (μM)
1 graphic file with name d2ra00067a-u48.jpg L21 NA NA 72 a
graphic file with name d2ra00067a-u49.jpg L22 NA NA
graphic file with name d2ra00067a-u50.jpg L23 NA NA
graphic file with name d2ra00067a-u51.jpg L24 NA NA
2 72 a
2a graphic file with name d2ra00067a-u52.jpg
65 = [Zn(L21)(H2O)] 65 2.89 126.00
2b graphic file with name d2ra00067a-u53.jpg
66 = [Zn(L22)] 66 3.10 189.00
2c graphic file with name d2ra00067a-u54.jpg
67 = [Zn(L23)] 67 16.10 NA
2d graphic file with name d2ra00067a-u55.jpg
68 = [Zn2(L24)2(Cl)2] 68 4.06 86.0
a

Not reported.