α-Glucosidase inhibitory activity of divalent metal complexes bearing diamine ligands.

Entry	Compounds	Structure number	IC50 (mg mL−1)	Ref.
1		L25	Not reported	74 a
		L26	Not reported	74 a
		L27	Not reported	75 b
		L28	Not reported	76 a
2	[Zn(L25)3].2Cl	69	298	74 a
	[Zn(L25)3].2NO3	70	278
	[Zn(L25)3]·SO4	71	305
	[Cu(L25)3]·2Cl	78	266
	[Cu(L25)3]·2NO3	79	279
	[Cu(L25)3]·SO4	80	256
	[Ni(L25)3]·2Cl	87	226
	[Ni(L25)3]·2NO3	88	198
	[Ni(L25)3]·SO4	89	218
3	[Zn(L26)3]·2Cl	72	1.19	74 a
	[Zn(L26)3]·2NO3	73	1.50
	[Zn(L26)3]·SO4	74	1.43
	[Cu(L26)3]·2Cl	81	1.33
	[Cu(L26)3]·2NO3	82	1.26
	[Cu(L26)3]·SO4	83	1.76
	[Ni(L26)3]·2Cl	90	3.63
	[Ni(L26)3]·2NO3	91	2.70
	[Ni(L26)3]·SO4	92	2.00
	[Co(L26)3]·Cl2	96	1348
	[Co(L26)3]·(NO3)2	97	1279
	[Co(L26)3]·SO4	98	1198
4	[Zn(L27)3]·2Cl	75	2.13	75 b
	[Zn(L27)3]·2NO3	76	1.05
	[Zn(L27)3]·SO4	77	2.0
	[Ni(L27)3]·2Cl	93	2.53
	[Ni(L27)3]·2NO3	94	1.74
	[Ni(L27)3]·SO4	95	1.93
	[Co(L27)3]·Cl2	99	1.20
	[Co(L27)3]·(NO3)2	100	0.90
	[Co(L27)3]·SO4	101	1.09
5	[Cu(L28)3]·2Cl	84	0.80	76 a
	[Cu(L28)3]·2NO3	85	0.47
	[Cu(L28)3]·SO4	86	0.61

^aAcarbose as the reference drug (IC₅₀ = 0.140 mg mL⁻¹).

^bAcarbose as the reference drug (IC₅₀ = 0.143 mg mL⁻¹).