. 2022 Feb 1;42(2):94–105. doi: 10.1002/phar.2656

TABLE 3.

Adverse effects by race and sex groups (n = 65)

Parameter ^a	Black females (n = 13)	Black males (n = 20)	White females (n = 16)	White males (n = 16)	p‐Values for the effect of			Significant pairwise comparisons (Tukey adjusted)
Parameter ^a	Black females (n = 13)	Black males (n = 20)	White females (n = 16)	White males (n = 16)	Race	Sex	Interaction of race and sex	Significant pairwise comparisons (Tukey adjusted)
Cumulative AE ratio ^c	0.21 (0.06)	0.09 (0.06)	0.16 (0.09)	0.13(0.06)	0.736	<0.001	0.014	BF vs. BM p < 0.001 BF vs. WM p = 0.012 BM vs. WF p = 0.018
GI AE ratio ^c	0.35 (0.17)	0.20 (0.18)	0.28(0.28)	0.26 (0.16)	0.866	0.139	0.140	—
Neurologic AE ratio ^b	0.33 (0.17)	0.13 (0.11)	0.200 (0.13)	0.22 (0.18)	0.646	0.021	0.005	BF vs. BM p = 0.002
Aesthetic AE ratio ^d	0.07 (0.08)	0.02 (0.04)	0.11 (0.13)	0.031 (0.05)	0.271	0.002	0.617	BM vs. WF p = 0.008 WF vs. WM p = 0.043

Significant p values are denoted by bold type.

Abbreviations: AE, adverse effect; B, Blacks; F, females; GI, gastrointestinal; M, males; W, White.

^{^a}

Data displayed as mean (standard deviation).

^{^b}

Parameters that were log transformed during statistical analysis.

^{^c}

Square root transformation of parameter.

^{^d}

Inverse transformation of parameter