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. Author manuscript; available in PMC: 2022 Apr 20.
Published in final edited form as: Hosp Physician. 1999 Jul;35(7):43–54.

Table 2.

Major and Minor Criteria for Diagnosis of Polycythemia Vera *

Major criteria (A)
A1: Erythrocyte mass greater than 36 mL/kg in men or greater than 32 mL/kg in women or packed cell volume > 0.51 in men and > 0.48 in women
A2: Splenomegaly
A3: Oxygen saturation greater than 92%
Minor criteria (B)
B1: Platelet count higher than 400,000/mm3
B2: Leukocyte count higher than 12,000/mm3 (no fever or infection)
B3: Leukocyte alkaline phosphatase score higher than 100
B4: Vitamin B12 level higher than 900 pg/mL or unsaturated vitamin B12-binding capacity higher than 2200 pg/mL
*

Diagnosis requires the presence of all three major criteria or two major criteria (excluding splenomegaly) and two minor criteria; for example, A1 + A2 + A3 or A1 + A3 + any two B.