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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: J Pediatr. 2021 Aug 25;239:168–174. doi: 10.1016/j.jpeds.2021.08.031

Table 2:

Associations between OSA and various biomarkers (log scale) adjusted for age, race, sex and body mass index (BMI) z score

Controls (n=53) (IQR) OSA (n=43) (IQR) Group Estimate (OSA vs control) (SE) Group estimate p

Adiponectin (μg/mL) 20.2 (13.4, 28.7) 18.8 (13.5, 29.6) −0.05 (0.13) 0.66
SAA (μg/mL) 1.5 (1.0, 3.2) 2.1 (1.1, 4.9) 0.04 (0.24) 0.87
sCD40L (pg/mL)* 0.95 (0.35, 2.95) 3.14 (1.11, 9.18) 0.94 (0.30) 0.002
IL-6 (pg/mL)* 7.0 (2.2, 27.2) 18.1 (6.0, 54.7) 0.73 (0.33) 0.03
IL-8 (pg/mL)* 5.4 (2.0, 8.4) 9.0 (4.1, 23.1) 0.62 (0.24) 0.01
MCP-1 (pg/mL) 92.0 (77.1, 109.0) 101.0 (86.7, 123.6) 0.06 (0.08) 0.48
TNF-α (pg/mL) 3.9 (2.6, 5.9) 5.2 (3.2, 8.8) 0.10 (0.23) 0.67
CRP (μg/mL) 0.27 (0.21, 0.55) 0.45 (0.23, 1.42) 0.44 (0.21) 0.04

n=number, IQR=interquartile range; CRP = C-reactive protein; IL = interleukin; MCP-1 = monocyte chemoattractant protein; OSA = obstructive sleep apnea; TNF-α = tumor necrosis factor.

*

p<0.05