. Author manuscript; available in PMC: 2022 Dec 1.

Published in final edited form as: J Pediatr. 2021 Aug 25;239:168–174. doi: 10.1016/j.jpeds.2021.08.031

Table 4.

Associations between OSA and markers ultrasound measures of carotid structure and function adjusted for age, race, sex and BMI z score

	Controls (n=53) (IQR)	OSA (n=43) (IQR)	Group Estimate (OSA vs no OSA) (SE)	Group estimate p
^aComposite Mean (cm)	0.039 (0.036, 0.042)	0.040 (0.036, 0.044)	.0002 (.001)	0.83
^bCommon Peak Systole Mean (cm)	0.58 (0.54, 0.61)	0.55(0.53, 0.59)	−.007 (.008)	0.37
^cCommon Peak Diastole Mean (cm)	0.48 (0.44, 0.50)	0.45 (0.43, 0.47)	−.012 (.007)	0.08
^dPeterson Common (mmHg/cm)	966.45 (793.77, 1158.04)	896.20 (755.34, 1073.92)	−26.62 (50.41)	0.60
^eMean lumen cross-sectional area (LCSA) (cm²)	0.18 (0.15, 0.20)	0.16 (0.14, 0.18)	−.0096 (.005)	0.07
^fMean wall cross-sectional area (WCSA) (cm²)	0.07 (0.06, 0.08)	0.07 (0.06, 0.08)	−.0007 (.002)	0.78

n=number, IQR=interquartile range

Composite Mean = Composite measurement of the mean of the R and L CCA distal far wall IMT measurement, R and L bifurcation far wall intima medial measurement, and R and L ICA proximal far wall intimal medical thickness measurement

Common Peak Systole Mean = Mean of R and L CCA diameter at peak systole

Common Peak Diastole Mean = Mean of R and L CCA diameter at end diastole

Peterson Common:

\begin{matrix} Mean \\ of \end{matrix} \frac{Systolic BP - Diastolic BP}{(\begin{matrix} (R CCA diameter peak systole - R CCA \\ diameter end diastole) * (mean R CCA \\ diameter peak systole) \end{matrix})} + \frac{Systolic BP - Diastolic BP}{(\begin{matrix} (L CCA diameter peak systole - L CCA \\ diameter end diastole) * (mean L CCA \\ diameter end systole) \end{matrix})}

Mean lumen cross-sectional area of common carotid = $(π {(d D)}^{2}) / 4$ ; Mean diastolic diameter $(dD) = \frac{(R d D + L d D)}{2}$ ; LdD is left and RdD is right common carotid artery diastolic diameter

Mean wall cross sectional area (WCSA) = $π (\frac{d D}{2} + I M T)$

R=right, L=left, CCA = common carotid artery, ICA = internal carotid artery