Table 1:

Clinical characteristics

	CMB Absent, n=138	CMB Present, n=58	p value
Age, years, mean (SD)	63.6 (14.4)	72.0 (13.0)	0.0002
Sex, female, n (%)	67 (49)	33 (57)	0.29
Race, n (%)
1. White	106 (77)	40 (69)	0.47
2. Black	31 (22)	17 (29)
3. Other	1 (1)	1 (2)
Ethnicity, Hispanic, n (%)	5 (4)	3 (5)	0.70
Past medical history, n (%)
1. Hypertension	100 (72)	52 (90)	0.009
2. Diabetes mellitus	50 (37)	20 (34)	0.82
3. Hyperlipidemia	44 (32)	27 (46)	0.05
4. Stroke	29 (21)	26 (45)	0.0007
5. Transient ischemic attack	7 (5)	7 (12)	0.12
6. Atrial fibrillation	11 (8)	15 (26)	0.0008
7. Coronary artery disease	29 (21)	15 (26)	0.46
8. Congestive heart failure	6 (4)	10 (17)	0.007
9. Peripheral vascular disease	4 (3)	0 (0)	0.32
Social history, n (%)
1. Tobacco use	74 (54)	27 (46)	0.37
2. Alcohol use	48 (35)	19 (33)	0.79
3. Illicit drug use	10 (7)	4 (7)	1.00
Medication history, n (%)
1. Antiplatelet	48 (35)	36 (62)	0.0004
2. Anticoagulants	7 (5)	6 (10)	0.18
3. Antithrombotic (antiplatelet or anticoagulant)	53 (38)	39 (67)	0.0002
Vitals sings, median (IQR)
1. Systolic blood pressure, mm Hg	152 (137–167)	163 (143–181)	0.003
2. Diastolic blood pressure, mm Hg	82 (71–93)	89 (76–100)	0.008
3. Body mass index, kg/m²	28 (24–33)	27 (23–31)	0.08
NIH stroke scale score, median (IQR)^†	4 (2–8)	3 (1–8)	0.80
TOAST classification, n (%)
1. Large artery disease	30 (22)	9 (16)	0.08
2. Cardioembolism	23 (17)	17 (29)
3. Small vessel occlusion	36 (26)	20 (34)
4. Other determined etiology	13 (9)	2 (3)
5. Undetermined etiology	36 (26)	10 (17)

SD = standard deviation; IQR = interquartile range;

^†

Missing NIH stroke scale for 12 and 3 patients in CMB absent and present group respectively;