Table 2:

Laboratory and imaging characteristics

	CMB Absent, n=138	CMB Present, n=58	p value
Laboratory characteristics
Lipid profile, mg/dl, median (IQR)^†
1. Low density lipoprotein	102 (68–131)	93 (72–120)	0.45
2. High density lipoprotein	45 (33–55)	48 (39–64)	0.02
3. Total cholesterol	174 (140–209)	171 (149–204)	0.96
4. Triglycerides	112 (81–164)	97 (73–131)	0.11
Complete blood count, median (IQR)
1. Hemoglobin, g/dl	14 (13–15)	14 (12–15)	0.14
2. Platelets, x10³/mL	217 (185–268)	209 (169–237)	0.10
Renal function, mg/dl, median (IQR)
1. Blood urea nitrogen	15 (10–19)	16 (12–21)	0.35
2. Creatinine	0.9 (0.7–1.1)	0.9 (0.8–1.1)	0.27
Coagulation profile, median (IQR)^‡
1. Prothrombin time, seconds	13 (13–14)	13 (13–14)	0.55
2. INR	1 (1–1.1)	1 (1–1.1)	0.50
3. Partial thromboplastin time, seconds	29 (27–32)	29 (27–32)	0.63
Hemoglobin A1c, %, median (IQR)^†	6.1 (5.6–7.4)	5.9 (5.5–6.4)	0.08
Imaging characteristics
Last known well to MRI, days, median (IQR)	1.07 (0.66 – 1.96)	0.90 (0.55 – 1.41)	0.03
Vascular Territory, n (%)
1. Anterior cerebral artery	10 (7)	4 (7)	1.00
2. Middle cerebral artery	89 (64)	43 (74)	0.19
3. Anterior choroidal artery	6 (4)	2 (3)	1.00
4. Posterior cerebral artery	27 (20)	16 (28)	0.22
5. Basilar artery	27 (20)	4 (7)	0.03
6. Vertebral artery	11 (8)	7 (12)	0.36
Fazekas scale score, n (%)
1. Periventricular hyperintensity
a) Score 0	21 (15)	4 (7)	<0.0001
b) Score 1	57 (41)	10 (17)
c) Score 2	44 (32)	21 (36)
d) Score 3	16 (12)	23 (40)
2. Deep white matter hyperintensity
a) Score 0	38 (28)	4 (7)	<0.0001
b) Score 1	67 (49)	18 (31)
c) Score 2	27 (20)	28 (48)
d) Score 3	38 (4)	8 (14)
3. Total Fazakas score
a) Score 0–3	104 (75)	20 (34)	<0.0001
b) Score 4–6	34 (25)	38 (66)

^†

Missing labs for 2 and 1 patients in CMB absent and present group respectively;

^‡

Missing labs for 21 and 14 patients in CMB absent and present group respectively

IQR = interquartile range;