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. 2022 Apr 8;18(4):e1010458. doi: 10.1371/journal.ppat.1010458

Table 2. Minimum Inhibitory Concentrations (μg/ml) of various antimicrobial peptides (AMPs) against the R6 and D39 strains.

R6 strain
AMPs WT ΔbceAB Δtcs01 ΔbceAB/tcs01 Fold sensitivity displayed by the KO strains
actagardin 32 2 2 2 16
bacitracin 8 1 1 1 8
nisin 3.2 0.4 0.4 0.4 8
Planosporicin (NAI-97) 16 2 2 2 8
NAI-802 16 2 2 2 8
Microbisporicin (NAI-107) 0.032 0.008 0.008 0.008 4
NAI-857 4 2 2 2 2
gramicidin 0.016 0.016 0.016 0.016 1
ramoplanin 0.02 0.02 0.02 0.02 1
vancomycin 0.5 0.5 0.5 0.5 1
mastoporan 32 32 32 32 1
colistin 256 256 256 256 1
D39 strain
AMPs WT ΔbceAB Δtcs01 ΔbceAB/tcs01 Fold sensitivity diplayed by the KO strains
bacitracin 4 1 1 1 4
nisin 3.2 0.2 0.2 0.2 16
actagardin 32 2 2 2 16
vancomycin 0.25 0.25 0.25 0.25 1
ramoplanin 0.03 0.03 0.03 0.03 1

Experiments were performed with two to four biological replicates, each with technical duplicates.