FIGURE 1.

Schematic representation of domains of FtsH2 from Synechocystis sp. PCC 6803. Annotations: transmembrane domain (TM), ATPase domain (AAA + ATPase) and protease domain (Protease) are illustrated as colored boxes. The TM domain includes two transmembrane helices (yellow) and a soluble linker exposed to the thylakoid lumen (blue). The soluble regions exposed to the cytoplasm include a flexible linker (green), ATPase (cyan), and protease domains (red). The amino-acid residues that separate each domain are labeled below the colored boxes. Annotated functional motifs include the proposed substrate entry point (FVG); ATP hydrolysis motifs Walker A and B, and the second region of homology (SRH); and the zinc-binding proteolytic site (HEXXH, X represents any amino acid).