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. 2022 Apr 6;13:837528. doi: 10.3389/fpls.2022.837528

TABLE 1.

Summary of the phenotypes from FtsH mutants of Arabidopsis thaliana.

Genotype FtsH location Phenotype Reference(s)
ftsH1 (typeA) null Thylakoid membrane WT-like phenotype Sakamoto et al., 2003; Zaltsman et al., 2005b
ftsH5 (type A) null Thylakoid membrane Weak leaf variegation (var1) Sakamoto et al., 2002; Wagner et al., 2011
ftsH1, ftsH5 null Thylakoid membrane Albino-like, embryo lethality, loss of photoautotrophic growth Yu et al., 2004, 2005; Zaltsman et al., 2005b
ftsH2 (type B) null Thylakoid membrane Yellow variegated 2 (var2)
severe leaf variegation
Chen et al., 2000; Takechi et al., 2000; Bailey et al., 2002; Wagner et al., 2011
ftsH8 (type B) null Thylakoid membrane WT-like phenotype Sakamoto et al., 2003; Zaltsman et al., 2005b; Wagner et al., 2011
ftsH2, ftsH8 null Thylakoid membrane Albino-like, embryo lethality, loss of photoautotrophic growth Yu et al., 2004, 2005; Zaltsman et al., 2005b
ftsH1, ftsH8 null Thylakoid membrane WT-like phenotype Zaltsman et al., 2005b
ftsH6 null Thylakoid membrane Enhanced heat-tolerance and thermomemory Sedaghatmehr et al., 2016
ftsH7 null Chloroplast envelope WT-like phenotype Wagner et al., 2011
ftsH9 null Chloroplast envelope Unknown Ferro et al., 2010; Wagner et al., 2011
ftsH12 null Chloroplast envelope Embryo lethality Ferro et al., 2010
ftsHi1 null Chloroplast envelope Embryo lethality Kadirjan-Kalbach et al., 2012; Mishra et al., 2019
ftsHi1 missense mutant Chloroplast envelope Pale seedling Kadirjan-Kalbach et al., 2012; Mishra et al., 2019
ftsHi2 null Chloroplast envelope Embryo lethality Schreier et al., 2018; Mishra et al., 2019
ftsHi3 null Chloroplast envelope Residual albino growth Kikuchi et al., 2018
ftsHi4 null Chloroplast envelope
or thylakoid membrane
Embryo lethality Lu et al., 2014; Mishra et al., 2019
ftsHi5 null Chloroplast envelope Embryo lethality Wang et al., 2018; Mishra et al., 2019
ftsH11 (i-AAA) null Chloroplast envelope Reduced heat-tolerance Urantowka et al., 2005; Chen et al., 2006; Wagner et al., 2011, 2016
ftsH4 (i-AAA) null Mitochondrial inner membrane Abnormal leaf morphology in late rosette development under short-day conditions Gibala et al., 2009; Wagner et al., 2011
ftsH3 (m-AAA) null Mitochondrial inner membrane WT-like phenotype Piechota et al., 2010; Wagner et al., 2011
ftsH10 (m-AAA) null Mitochondrial inner membrane WT-like phenotype Piechota et al., 2010; Wagner et al., 2011
ftsH3, ftsH10 null Mitochondrial inner membrane Decreased size of seedlings and developmental delay Kolodziejczak et al., 2018