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Macklin effect in a COVID-19 patient. Lung parenchyma windowed CT images demonstrate [a] a crescent collection of air contiguous to the middle lobar bronchovascular sheath as well as interstitial emphysema in the left upper lobe, both representing Macklin effect (red arrows). Seven days later [b], pneumomediastinum occurred. . (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
