Table 1.

Baseline characteristics and clinical course of the 33 patients with Macklin effect on baseline chest CT scan.

Variable	Value (N = 33)
Patients Characteristics
➢Male sex, n (%)	23 (69.9)
➢Age, years	65.8 ± 8.6
➢BMI, kg/m2	29.4 ± 5.3
Comorbidities
➢Hypertension, n (%)	11 (39.3)
➢Cardiovascular disease (excluding hypertension), n (%)	9 (27.2)
➢Diabetes, n (%)	10 (30.3)
➢COPD, n (%)	10 (30.3)
➢CKD, n (%)	2 (6.1)
➢Malignancy, n (%)	5 (15.1)
O2 supplementation at the time of the first CT scan
➢No supplemental oxygen, n (%)	0 (0)
➢Supplemental oxygen (FiO2 0.50 to 0.80), n (%)	33 (100)
➢Non-invasive ventilation/CPAP, n (%)	0 (0)
➢Invasive ventilation	0 (0)
Barotrauma characteristics
➢At least one barotrauma event, n (%)	32 (96.9)
➢Pneumomediastinum alone, n (%)	14 (42.4)
➢Pneumothorax alone, n (%)	8 (24.2)
➢Pneumomediastinum and pneumothorax, n (%)	10 (30.3)
➢Subcutaneous emphysema, n (%)	11 (33.3)

BMI: body mass index; CKD: chronic kidney disease; COPD: chronic obstructive pulmonary disease; CPAP: continuous positive airway pressure; ICU: intensive care unit; SpO₂: peripheral oxygen saturation; °C: Celsius degrees.