Table 1.

Novel and conserved insect-derived miRNAs and their immune targets.

Insect	miRNA	Target gene	Expression level	Host target	Ref.
G. mellonella	gme-new-135-3p	TNF-8-like	–	G. mellonella	(136)
	gme-miR-274-3p	TNF-8-like	–
	gme-miR-8-5p	TNF-8-like	–
	gme-new-161-3p	Poly(A)-pol	–
	gme-new-160-5p	zf-LITAF-like	Up
	gme-new-135-5p	Invertebrate-type lysozyme	–
	gme-miR-263a-5p	Invertebrate-type lysozyme	–
	gme-new-70-3p	Linear gramicidin synthase subunit D	–
	gme-new-147-3p	Long-chain-fatty-acid CoA ligase 5	–
	gme-new-54-3p	Ras guanine-nucleotide exchange factor	–
	gme-new-40-3p	phosphatidylinositol 3-kinase	Up
	gme-new-138-3p	AMP-dependent synthetase/ligase	Up
	gme-new-72-3p	Atlastin	–
	gme-new-4-5p	Long-chain-fatty-acid-CoA ligase 4	–
	gme-new-135-3p	Long-chain-fatty-acid-CoA ligase ACSBG2	–
Drosophila	miR-959	Tube	Down	Drosophila	(137)
	miR-960	Tube	Down
	miR-961	Dorsal	Down
	miR-962	Dorsal	Down
	miR-962	Toll	Down
	let-7	sec2p	Down	B. bassiana	(23)
	miR-100	C6TF	Down
A. aegypti	miR-2b	URM	Down	A. aegypti	(26)