Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetic parameters after subcutaneous administration of GM193663 and GM237354 to mice and ratsa
| Species | Compound | Dose (mg/kg) | Cmax (μg/ml) | AUC (μg · h/ml) | t1/2 (h) | CL (ml/h) |
|---|---|---|---|---|---|---|
| Mouse | GM193663 | 50 | 51.8 | 79.5 | 0.8 | 21 |
| GM237354 | 50 | 23 | 46 | 0.85 | 25 | |
| Rat | GM193663 | 10 | 6.6 | 8.5 | 0.7 | 230 |
| GM237354 | 10 | 7.2 | 11.8 | 0.8 | 133 |
Values are means for three animals.
