Table 5.

WGS data for K. pneumoniae and E. coli isolates from Kuwait and Oman

Isolates stratified by country	IHMA number	C/T MIC (mg/L)	OmpC-like	OmpF-like	PBP3(ftsI)a	β-Lactamase summary (72% identity; 80% coverage)b	MLST
Kuwait
1. K. pneumoniae	1562167	16	No lesion	No lesion	WT	CTX-M-15; OXA-1; OXA-48; SHV-1-like; TEM-1B	831
2. K. pneumoniae	1572948	>32	No lesion	No lesion	WT	CTX-M-15; NDM-1; OXA-9-like; SHV-11; TEM-1B	336
3. K. pneumoniae	1724041	>32	Frameshift, 70 AA protein	No lesion	WT	CTX-M-15; OXA-1; SHV-83; TEM-1B-like	985
Oman
1. K. pneumoniae	1688174	16	No lesion	Frameshift, 212 AA protein	WT	CTX-M-15; OXA-1; SHV-1; TEM-1B	1658
2. K. pneumoniae	1688181	>32	No lesion	Frameshift, 107 AA protein	WT	CTX-M-15; OXA-232; SHV-ESBL; TEM-1B	231
Kuwait
1. E. coli	1572932	>32	No lesion	No lesion	E149D; T233A; V332I; 3331NS-YR1K; A413V	CMY-7-like; EC-like; TEM-34-like	7395
2. E. coli	1723961	8	No lesion	No lesion	E149D; Q227H; T233A; V332I; 3331NS- YR1N; E349K; 1532L	CTX-M-15; EC-like; OXA-1-like; TEM-1B	361
3. E. coli	1734194	>32	No lesion	No lesion	E149D	CTX-M-15; EC-like; TEM-1B	131

AA, amino acid; C/T, ceftolozane/tazobactam.

^aAmino acid changes are greater relative to reference sequences.

^bThreshold for β-lactamase gene inclusion was 72% and 80% for minimum nucleotide sequence identity and minimum sequence length, respectively.

^cNovel MLSTs were given sequential designations for clarity.